Mark S. Slaughter, , M.D.


PHONE 502-561-2187

FAX 502-561-2190



Mark Slaughter, M.D., an internationally acclaimed expert in heart transplants and ventricular assist devices (VAD), is the director of the Heart Transplant and Mechanical Assist Device program at Jewish Hospital & St. Mary’s HealthCare, as well as chief of the department of Thoracic and Cardiovascular Surgery for the University of Louisville.

After receiving his medical degree from the Indiana University School of Medicine, Dr. Slaughter completed his general surgery residency at McGaw Medical Center of Northwestern University in Chicago, and his cardiovascular and thoracic surgery fellowship at the University of Minnesota Hospital and Clinic. He is certified by the American Board of Surgery and American Board of Thoracic Surgery.

Prior to leaving Chicago’s Advocate Christ Medical Center and the University of Illinois in 2008, Dr. Slaughter implanted over 250 ventricular assist devices and was a leader in destination therapy, or permanent use of the device for patients who aren’t transplant eligible. His work has also focused on using the VAD as a bridge to transplant, as well as for myocardial recovery and rescue surgeries.

Dr. Slaughter has published over 50 articles, has written a book, and chapters in multiple books. He serves on the board of directors for the American Society of Artificial Internal Organs (ASAIO), board of trustees for the International Society of Rotary Blood Pumps, the editorial board of ASAIO and is a journal reviewer for the Annals of Thoracic Surgery, Circulation and the Journal of Heart and Lung Transplantation.

Dr. Slaughter currently serves as a consultant to the FDA Medical Device Review panel and a National Science Foundation SBIR/STTR grant reviewer, and has previously served two terms for the Health and Human Services Medicare Coverage Advisory committee.

In addition to being substantially active in clinical trials and manuscript contributions, Dr. Slaughter is committed to training future leaders in thoracic surgery.

Since Dr. Slaughter’s arrival, Jewish Hospital has become the second hospital in the nation (and first in Kentucky) to implant the HeartWare Ventricular Assist System as part of a national clinical trial. The implant procedure was performed by Dr. Slaughter, the principal investigator in the trial, and was completely successful. HeartWare’s HVAD pump is the only full-output pump designed to be implanted in the chest, avoiding the abdominal surgery generally required to implant competing devices.

Dr. Slaughter’s overlying goal is to offer individuals with heart failure an alternative to heart transplantation, repairing hearts and helping them recover naturally, without the need of a transplant.

Curriculum Vitae